Zymosan Manufacture Service
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Structure of Zymosan
Zymosan is a naturally occurring water-insoluble macromolecule extracted from the cell wall of Saccharomyces cerevisiae, and is the main component of the cell wall. The structure of zymosan consists of repeating glucose units linked by beta-(1,3)-glycosidic bonds, showing a unique triple ultra-helix which gives it the strongest immune activity.
Fig.1 Saccharomyces cerevisiae and the beta-(1,3)-glucose unit of zymosan. (Wikipedia)
Applications of Zymosan
- Immune activator: Zymosan is the first polysaccharide discovered and used to enhance immunity, which activates both innate and acquired immunity by enhancing the functions of macrophages and natural killer cells.
- Functional food (dietary fiber): Zymosan promotes intestinal peristalsis, absorb harmful substances in the intestine, and promote the activation of helpful bacteria in the intestine.
- Food additives: With strong water retention, emulsification stability, and high viscosity, zymosan is added to seasonings, desserts, meat products, etc.
- Lowering cholesterol levels: Zymosan promotes the transformation of cholesterol into bile acid and maintains the normal metabolism of cholesterol.
- Animal feed: Zymosan acts as a natural immune enhancer that can replace antibiotics to enhance non-specific immunity in animals.
- Cosmetics: With anti-infection, anti-radiation, and immunity-enhancing effects, zymosan is used in shampoo, shower gel, facial cleanser, sunscreen, and other cosmetic products.
Zymosan Manufacture Service
Zymosan has good application prospects in medicine, food, animal feed, cosmetics, and other industries, with great research value and commercial value. CD BioGlyco is well-versed in various zymosan extraction strategies, the extraction methods we offer include but are not limited to:
- Acid/Alkali extraction: Treat materials with a hot acidic or alkaline solution, centrifuge and collect the precipitate, dehydrate with anhydrous ethanol, dry, and obtain finished products. The use of the method can achieve rapid and efficient extraction of zymosan.
- Enzymatic Extraction: Treat the cell wall of Saccharomyces cerevisiae with suitable enzymes (protease) and obtain zymosan. The extraction conditions are mild and environmentally friendly.
- Oxidated extraction: Directly oxidate the cell wall of Saccharomyces cerevisiae with sodium hypochlorite and release zymosan. The method has been thoroughly studied by researchers, and zymosan with high purity can be obtained.
- Complex extraction methods: Enzymolysis-alkali extraction and enzymolysis-ultrasound-assisted extraction can effectively improve the yield of zymosan, reduce the protein content, and ensure the complete glucan chains and biological activity of the product.
Zymosan is poorly soluble in water, which greatly limits its application. Therefore, obtaining soluble beta-glucan is an important prerequisite for further research and development of zymosan. CD BioGlyco provides different derivatization methods:
- Chemical modification: Carboxymethylation and sulfation are commonly used chemical derivatization methods.
- Depolymerization: Acid/Base hydrolysis, enzyme degradation, ultrasonic, and heat treatment alone or in combination can be used to depolymerize zymosan, reduce its molecular weight, and obtain low molecular weight glycan fragments.
Highlights
- Multiple and selectable strategies for zymosan extraction
- Product with molecular integrity and high biological activity.
- Large-scale production capacity
To help researchers investigate and apply zymosan in various fields and realize the in-depth development of zymosan, CD BioGlyco provides high-quality zymosan manufacture service in a short time. Our products undergo rigorous testing to ensure purity, complete molecular chain, and biological activity. We also provide Other Beta-Glucan Manufacture Services. If you are interested in our services, please contact us for more information.
For research use only. Not
intended for any clinical use.
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