Technologies for Carbohydrate Derivative Manufacture

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Characteristics of Carbohydrate Derivatives

Carbohydrates, also known as sugar compounds, are composed of three elements: carbon, hydrogen, and oxygen. Carbohydrates are the most abundant and widely distributed class of important organic compounds in nature. It is the main source of energy needed by all living organisms to maintain their life activities, so it plays an important role in human health. In addition, carbohydrate derivatives are also very important, and they have some special physiological activities, such as maintaining the normal function of brain cells, composing cells and tissues, conserving proteins, and detoxification. To expand the applications of carbohydrate derivatives, it is effective to use chemical or biological techniques to modify the structure of conventional carbohydrate derivatives. The new carbohydrate derivatives obtained often have more excellent properties and wider application prospects.

Our Technologies

Based on the excellent properties of carbohydrate derivatives, a great deal of research has been done on how they are synthesized. At CD BioGlyco, we offer several technologies to produce carbohydrate derivatives.

Natural Extraction

We use polar solvents such as water and lye to extract carbohydrate derivatives. In addition to this, we offer enzymatic extraction, microwave extraction, ultrasonic extraction, subcritical water, and electric field extraction. In the meantime, we will also provide dialysis, membrane filtration, organic reagent precipitation, and ion exchange resins to remove small molecule mixtures.

Chemical Synthesis

At CD BioGlyco, we synthesize complex carbohydrate derivatives with glycosylation reactions at the core. The main principle of this reaction is to assemble sugar building blocks, which in turn form complex glycan structures. For the assembly of glycans, CD BioGlyco offers orthogonal selective liquid-phase one-autoclave synthesis strategies, programmed liquid-phase one-autoclave synthesis strategies, pre-activated liquid-phase one-autoclave synthesis strategies, and automated solid-phase synthesis strategies to carry out the process.

Enzymatic Conversion

Enzymes have high catalytic activity, are reusable and non-toxic. To produce better-performing carbohydrate derivatives, CD BioGlyco immobilizes the enzymes as well as directionally mutates them. Secondly, we also combine chemical and enzymatic methods to produce carbohydrate derivatives.

Microbial Fermentation

Microorganisms are a renewable resource capable of producing carbohydrate derivatives. At CD BioGlyco, we produce complex carbohydrate derivatives based on the fermentation of microorganisms, including bacteria and fungi. However, whether it is bacteria or fungi, we offer both liquid fermentation and solid fermentation methods to produce carbohydrate derivatives.

Production technology for carbohydrate derivatives.Fig.1 Production technology for carbohydrate derivatives. (CD BioGlyco)

Applications

  • In the medical field, carbohydrate derivatives are applied to the manufacture of drugs that lower blood sugar.
  • In the food processing field, carbohydrate derivatives are used in the development of healthy food products that can replenish the body's energy.
  • Part of the lubricating effect of carbohydrate derivatives can be applied to the synthesis of precursors of biomolecules.

Advantages

  • Our carbohydrate derivatives manufacturing technology helps researchers to explore the physiological functions of biological macromolecules (e.g. purines, sterols, etc.).
  • We have a wide range of carbohydrate derivatives manufacturing technologies and provide different manufacturing solutions according to the different needs of our customers.
  • Various types of manufacturing technologies help to further explore the physiological functions of carbohydrate derivatives. For example, lowering blood sugar.

CD BioGlyco has a specialized research team to provide comprehensive services to our customers for the production of carbohydrate derivatives. We will customize different types of production solutions for our clients according to their specific needs. If you are interested in our services, please do not hesitate to contact us.

Reference

  1. Li, H.; Tang, S.Y. Carbohydrate-binding modules: assisted polysaccharide recognition. Acta Microbiologica Sinica. 2017, 57(8): 1160-1167.
For research use only. Not intended for any clinical use.

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