The Structure of Splitgill Mushroom Beta-Glucan

Splitgill mushroom beta-glucan was first isolated from a non-edible plant-parasitic fungus, Schizophyllum commune. The main chain of the beta-glucan monomer consists of three (1→3) linked glucose, with one glucose unit connected to the middle sugar by (1→6) bond. Its molecular weight is between 100 and 200 kDa. The molecule shows a triple helix conformation in an aqueous solution, similar to lentinan. Schizophyllan is a water-soluble and extracellular polysaccharide. Pharmacologically, the split-gill mushroom is extremely important. It produces the polysaccharide schizophyllan which shows considerable medicinal properties having capable factors for the prevention of several human infirmities.

Fig.1 The structure of splitgill mushroom beta-glucan. (Vetter, et al., 2023)

Splitgill Mushroom Beta-Glucan Manufacture Services at CD BioGlyco

CD BioGlyco provides the service of separating and extracting high-quality β-Glucan from splitgill mushrooms. According to your needs, splitgill mushroom β-glucan is separated and purified by different extraction processes. The services we provide include but are not limited to the following aspects:

• Multiple methods for the extraction

Separate polysaccharides from their fruiting bodies, mycelium or fermentation broth, while keeping the original spatial structure of the polysaccharides unchanged. Two types of extraction methods are provided:

• Traditional extraction process

Enzymatic extraction, hot water extraction, and dilute alkali extraction are traditional extraction methods widely used. With water as a solvent, β-glucan can be extracted from hot or cold water and treated with hydrochloric acid or acetic acid, generally with sodium borohydride or potassium borohydride as a solvent.

• New extraction process

Newer extraction processes such as ultrasonic extraction, microwave extraction, flash extraction, or compound enzymatic methods, mainly use new technologies or auxiliary means to improve extraction efficiency and have broad application prospects. The biological activity of schizophyllan can be changed and improved by ultrasonic treatment of the molecule.

• Other services

If you want Custom Beta-Glucan Manufacture, rest assured that we have a perfect technical team, and the most advanced instruments in the field of Carbohydrate Manufacture to meet all your requirements.

Applications

• Splitgill mushroom beta-glucan can be potentially used against head and neck cancer, resulting in improved patient survival.
• Silver nanoparticle composites are prepared for wound healing.
• Splitgill mushroom beta-glucan is an important ingredient of pesticides.
• With bacteriostatic, anti-inflammatory, and moisturizing effects, splitgill mushroom beta-gluca can be used as a new biological flocculant material.

CD BioGlyco has accumulated rich experience in Polysaccharide Manufacturing and structure elucidation. We are recognized for providing high-quality services to customers in many countries. Please feel free to contact us, we will reply as soon as possible.

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