Acid-Base Extraction Service
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Applications of Acid-Base Extraction
Acid-base-based extraction methods utilize the solubility properties of polysaccharides under acidic or alkaline conditions to facilitate their extraction by adjusting the pH value to dissolve or precipitate them out of the biological material. This optimizes yield and purity by selecting appropriate acid-base conditions based on their specific properties. The acid-base-based technology finds diverse applications in fields like food, medicine, and bioengineering. In the food industry, they serve as additives, functioning as thickeners, gelling agents, and moisturizers, enhancing flavor, texture, and product quality. Moreover, they exhibit beneficial physiological activities making them valuable for drug development in the medical field. Additionally, as biodegradable materials, they hold promise for environmental protection and regenerative medicine applications in the realm of bioengineering.
Acid-Base Extraction Service at CD BioGlyco
CD BioGlyco offers you a comprehensive one-stop Polysaccharide Manufacturing Service and provides you with acid-base-based extraction service. The process of our service is as follows:
Preparation of Raw Materials and Extraction Solution
First, biological materials that contain the target polysaccharide, like plants, fungi, or animal tissues, need to be prepared. The biological material is pulverized to increase its surface area for easy dissolution and extraction processes. A suitable acid or base is selected to construct the extract according to the nature of the target molecules. If the molecule exhibits solubility in an acidic environment, an acidic extract should be selected. Conversely, an alkaline extract should be selected when the molecule exhibits solubility under an alkaline environment. The pH of the extract is adjusted to an appropriate acid-base environment to induce solubilization or precipitation of the target molecule.
Extraction Process
The pulverized and processed biomaterials are added to the pH-adjusted extraction solution and stirred or soaked thoroughly to dissolve or precipitate the glycan into the extraction solution. The biomaterial residue is removed by centrifugation, filtration, or precipitation to obtain an extract containing polysaccharides.
Post-Treatment
The extract is concentrated and the solvent is removed to concentrate the product within a certain volume range. Subsequently, the product is further purified by gel filtration, ultrafiltration, ion exchange, or other purification methods. The purified solution obtained is dried to obtain a solid polysaccharide product. Finally, the product is stored in a dry, airtight container to avoid moisture and contamination.
Fig.1 Process of acid-base extraction service. (CD BioGlyco)
Applications
- Polysaccharides have the functions of enhancing immunity, antioxidant, anti-tumor, and anti-aging, and are widely used in the field of medicine and health care products.
- Polysaccharides can be used in the preparation of herbal extracts, pharmaceutical formulations, and nutraceuticals.
- The biocompatibility and degradability of polysaccharides have led to the use of materials for cellular scaffolds, tissue repair, and drug slow release.
Advantages of Us
- Our extraction technology utilizes different raw material sources to extract polysaccharides for a wider range of applications and to meet specific needs.
- Our experts thoroughly evaluate the experimental program and design a suitable experimental procedure based on the source of the experimental material and the client's needs.
At CD BioGlyco, we leverage our expertise to provide our clients with high-quality polysaccharide extraction services utilizing the acid-base processes to effectively extract from various sources. If you are interested in our services, please contact us for more details.
References
- Tang, W.; et al. Consecutive and progressive purification of food-derived natural polysaccharide: based on material, extraction process and crude polysaccharide. Trends in Food Science & Technology. 2020, 99: 76-87.
- Huang, G.; et al. Preparation, deproteinization and comparison of bioactive polysaccharides. Trends in Food Science & Technology. 2021, 109: 564-568.
For research use only. Not
intended for any clinical use.
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