The Physiological Effects of Fructooligosaccharides

Fructooligosaccharides are derived from plants. The terminal fructose is connected to a glucose residue through β-(1→2) glycosidic bonds, forming a nonreducing sucrose end. Fructooligosaccharides have a degree of polymerization <10. Fructooligosaccharides display diverse amazing effects, such as low sweetness intensity. In addition, they possess zero calories, non-cariogenic effects, and are recognized as soluble dietary fiber. Besides, fructooligosaccharides possess crucial beneficial biological properties including low carcinogenicity and prebiotic effect. Moreover, they have effects on improving mineral absorption and reducing levels of serum cholesterol, triacylglycerols, and phospholipids. Presently, fructooligosaccharides are added to food products and infant formulas more frequently. Because their prebiotic effects promote the growth of beneficial intestinal microflora and inhibit the growth of harmful bacteria. The intake of fructooligosaccharides helps increase the size of fecal bolus and enhance bowel movement frequency.

Fig.1 The effects of fructooligosaccharides. (Pengrattanachot, et al., 2022)

Fructooligosaccharide Manufacture Service at CD BioGlyco

CD BioGlyco provides fructooligosaccharide manufacturing service by utilizing immobilization techniques for the Enzymatic Conversion.

Fructooligosaccharide is produced from sucrose by the action of fructosyl transferase (FTase) from Aureobasidium pullulans. We produce fructooligosaccharides continuously by A. pullulans immobilized on calcium alginate beads with a packed bed at a plant-scale reactor.

The packed bed reactor continuously produces fructooligosaccharides while reducing the product inhibition caused by the accumulation of glucose. The reactor is continuously supplied with an upward flow of sucrose solution. The reactor is charged with alginate beads. To maintain a constant temperature, hot water is circulated through the jacket surrounding the reactor. To ensure the continuous production of fructooligosaccharides, we employ an in-house bead-forming apparatus to mass-produce calcium alginate bead-immobilized cells. Specifically, we evenly distribute a thousand needles on the bottom of the stainless steel vessel. After thorough mixing, the cell-alginate mixture is poured into the vessel. Pressure is then exerted to propel the mixture through the needles. Upon entering the CaCl₂ solution, the resulting drops transform into calcium alginate beads. The storage tank containing the calcium alginate gel is gently fluidized with air in order to prevent bead crush or breakage caused by hydrostatic pressure within the tank.

Fig.2 The process of fructooligosaccharide manufacture. (CD BioGlyco)

Applications

Fig.3 The applications of fructooligosaccharides. (CD BioGlyco)

Advantages of Us

• Our approach produces fructooligosaccharides, reducing the product inhibition caused by the accumulation of glucose.
• Our strategy produces fructooligosaccharides in large quantities.
• Our production efficiency is exceptional, demonstrating superior performance in comparison to our competitors.

CD BioGlyco specializes in providing comprehensive Oligosaccharide Manufacture Services. With our expertise and outstanding research team, we ensure a superior and efficient manufacturing process for all your carbohydrate needs. CD BioGlyco delivers top-quality results and unmatched customer satisfaction in fructooligosaccharide production. Don't hesitate to contact us if you're interested in our services.

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