Overview of Carbohydrate Derivatives

Carbohydrates contain storage (e.g., starch), structural (e.g., cellulose, arabinoxylan, pectin), and other types that have important implications for human diet and health. Like proteins and nucleic acids, carbohydrates are a class of biomolecules that are very important in the life activities of the organism. It is involved in such life activities as fertilization, cell growth, cell-cell recognition, immune response, viral replication, and inflammatory response. Therefore, the role of carbohydrates in life sciences is very important. Polysaccharides usually refer to long-chain polymers formed by multiple monosaccharides linked together by glycosidic bonds. They are widely found in plants, animals, and microorganisms (fungi and bacteria). In recent years, a large number of studies have reported that polysaccharides have the functions of immunomodulation, intestinal flora regulation, antitumor, antioxidant, and hypoglycemic.

Our Technologies

The isolation and purification of naturally derived carbohydrates as well as structural characterization is an important area of research. CD BioGlyco provides naturally derived carbohydrate-based isolation purification and structural characterization services.

Fig.1 Natural extraction-based carbohydrate derivative manufacture and characterization service. (CD BioGlyco)

• Separation and purification

We provide different separation and purification techniques according to the different structures of carbohydrate derivatives. Before extraction, we use maceration to remove lipids and pigments.

• Extraction methods

In most cases, carbohydrate derivatives are polar macromolecules, so they can be extracted with polar solvents such as water and lye (heteropolysaccharides can be extracted with DMSO).

• Auxiliary methods of extraction

In addition, the auxiliary methods of extraction include enzyme-assisted extraction, microwave-assisted extraction, ultrasound-assisted extraction, subcritical water extraction, and electric field-assisted extraction.

To remove the mixture of small molecules entrapped in it, we provide dialysis, membrane filtration, organic reagent precipitation, and ion exchange resin. Finally, free proteins in carbohydrate derivatives can be removed using proteases, savage reagents, and acetic acid derivatives.

• Structural characterization

Most of the carbohydrate derivatives are structurally complex and therefore their structural characterization requires the use of a combination of techniques. The test methods we offer for structural characterization are shown in the table below (Table 1).

Table 1 Carbohydrate derivatives-based technical services. (CD BioGlyco)

Applications

• Used in the production of food additives
• Used as a carrier for the research of drugs

CD BioGlyco has a professional research team to provide a One-Stop Solution for the isolation, purification, and structural characterization of carbohydrates. We have a variety of methods for isolation and purification as well as structural characterization, and all of our methods have been repeatedly validated. If you are interested in our services, please feel free to contact us.

• Chemical Synthesis-based Carbohydrate Derivative Manufacture Service
• Enzymatic Conversion-based Carbohydrate Derivative Manufacture Service
• Microbial Fermentation-based Carbohydrate Derivative Manufacture Service