Bacterial Fermentation Process for the Production of Glycolipids

Glycolipids are lipid compounds containing sugar-based ligands, which are widely found in various organisms. It is a class of non-toxic, odorless, easily biodegradable biosurfactants, which are widely used in food, chemical, agriculture, and other fields. Currently, available glycolipid surfactants are mainly alginate glycolipids, rhamnolipid (RL)s, acacia glycolipids, mannose erythritol lipids, etc., of which RLs are the most widely studied.

Glycolipid production is mainly based on fermentation, of which bacterial fermentation can manufacture RL. RL is a kind of anionic biosurfactant, which is mainly generated through the fermentation of pseudomonas. RLs occur naturally in water, soil, and plants. They can be used as an active ingredient in body lotions and detergents, as well as in oil extraction, environmental remediation, agriculture, etc. Currently, Pseudomonas is used to produce RLs using different carbon sources.

Services

CD BioGlyco focuses on optimizing the bacterial fermentation process to maximize glycolipid yield and purity. We have automated production lines and our glycolipid manufacturing services include the following:

• Bacterial fermentation process services
  Our process research includes four steps: strain screening, process optimization (fermentation culture optimization, process strain optimization, etc.), RL extraction, and quality testing. Since raw materials are usually expensive, the process yield directly affects the production cost. Therefore, optimizing the process to increase the yield of RLs is the key to achieving the commercial development of RLs. We optimize the process. In terms of yield, wild strains produce lower amounts of RLs. We also improve RL production by targeted modification of production strains.

Fig.1 Direction of bacterial fermentation process optimization. (CD BioGlyco)

• RL production services (50,000 tons per year of RL)
  RL is a biosurfactant with the longest research time and the most mature application technology. Compared with traditional chemical surfactants, RLs have many advantages, such as salt resistance, temperature resistance, easy degradation, and so on. RLs are mainly produced through liquid fermentation, the overall fermentation process is green and pollution-free. The purity and quality of the product are extremely high. We provide different specifications of RLs that can be used in food and daily chemicals.

Applications

• Used in the growth of crops, vegetables, fruits, etc., RL can stimulate growth, assist in the absorption of nutrients, etc.
• In food, RL is mostly used as a bulking agent and flavoring agent to increase baking volume.
• In medicine, GL synthesis technology is used to make some GL with the ability of antibacterial, anti-tumor, anti-virus, and so on.

Advantages

• We specialize in strain improvement, optimization of fermentation parameters, and other technical operations to minimize various problems such as foaming during fermentation.
• We carry out relevant research around the selection and breeding of high-yielding strains and the optimization of fermentation processes.
• The preparation time of the fermentation process has been greatly reduced and the yield of RL has been increased.

CD BioGlyco continuously improves the quality and competitiveness of its products and controls all aspects of production. As a comprehensive supplier in the field of biosciences, we optimize bacterial fermentation processes. In addition, we offer Yeast Fermentation Process-based Glycolipid Manufacture Service and Enzymatic Post-Treatment-based Glycolipid Manufacture Service. If you need to know more about the process, please feel free to contact us.

• Yeast Fermentation Process-based Glycolipid Manufacture Service
• Chemical Post-Treatment-based Glycolipid Manufacture Service
• Enzymatic Post-Treatment-based Glycolipid Manufacture Service